Fractionation of proteins by electrical means

Details Fractionation of proteins by electrical means Fractionation of proteins by electrical means

1974-05-06

1976-08-03

Mack, John H.

Chemistry: electrical and wave energy

Processes and products

Electrostatic field or electrical discharge

204180R, B01K 500

Patent

active

039727912

ABSTRACT:
A process for the fractionation of liquid solutions of protein mixtures which includes the steps of subjecting such solutions to electrodialysis in the pH range 4.8 to 6, until desalting of the solution commences, said electrodialysis being conducted at temperatures below 15.degree.C; and continuing said electrodialysis until the specific resistance of the mixture exceeds 1000 ohm-cm whereby a fraction of said protein mixture precipitates; and recovering the dialysate. Another aspect of the invention is an albumin concentrate for use in the preparation of plasma extenders, having at least 90% albumin, free from salts, euglobulins and euglobulin-like materials.

REFERENCES:
patent: 3325389 (1967-06-01), Parsi et al.
patent: 3330749 (1967-07-01), Kuwata et al.
patent: 3497438 (1970-02-01), Badgley
patent: 3767548 (1973-10-01), Okada et al.
patent: 3829370 (1974-08-01), Bourat

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