Fluorinated polyenes

Details Fluorinated polyenes Fluorinated polyenes

1981-06-29

1982-06-15

Siegel, Alan

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

424275, 424285, 549497, 549498, C07D33316, C07D30712, A61K 3138, A61K 3134

Patent

active

043352480

ABSTRACT:
9-Substituted, 4- or 6-fluorine substituted retinoic acid derivatives useful as antitumor agents and in the treatment of acne as well as a method for their manufacture are disclosed. Substituents at the 9-position include substituted phenyl, thienyl and furyl groups.

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Englert, Hevl. Chim. Acta, 58:2367-2376, (1975).
Wilkoff et al., Cancer Research, 36:964, (1976).
Chem. Abst. 82:111778x, (1975).

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