Dihydro-dibenzoxepines-thiepines and -morphanthridones, composit

Details Dihydro-dibenzoxepines-thiepines and -morphanthridones, composit Dihydro-dibenzoxepines-thiepines and -morphanthridones, composit

1981-03-18

1982-06-15

Ramsuer, Robert W.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

42424851, 42424853, 42424854, 42424855, 42424858, 4242484, 424267, 424274, 424275, 424278, 544145, 544147, 546196, 546202, 549 12, 549349, 2602393T, 2603303, 2603309, 548525, A61K 31335, A61K 3155, C07D22320, C07D31312

Patent

active

043351220

ABSTRACT:
The invention relates to diuretic dihydro-dibenzoxepines-thiepines and -morphanthridones of the formula ##STR1## wherein R is ##STR2## where R.sup.4 is a hydrogen or an alkyl; R.sup.1 is hydrogen or alkyl; R.sup.2 and R.sup.3 are the same or different and are hydrogen, alkyl or R.sup.2 and R.sup.3 are fused to form a pyrrolidino, morpholino, piperidino or azepino ring substituent; Y is hydrogen, halogen and alkoxy, X is ##STR3## where R.sup.4 is as defined above; m is an integer of 0 or 1; and n is an integer of 2 or 3; and the pharmaceutically acceptable acid addition salts thereof.

REFERENCES:
patent: 3084155 (1963-04-01), Winthrop et al.
patent: 3420851 (1969-01-01), Bloom et al.
patent: 3609167 (1971-09-01), Zirkle
patent: 3639423 (1972-02-01), Winter et al.
patent: 4000288 (1976-12-01), Ackrell
Murakami et al., Chem. Abstracts, vol. 80 (1974) No. P3402v.
Nipgata et al., Chem. Abstracts, vol. 83 (1975) No. P114,249g.

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