Carboline histamine H.sub.1 antagonists

Details Carboline histamine H.sub.1 antagonists Carboline histamine H.sub.1 antagonists

1987-02-26

1988-06-28

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546 85, 546 86, C07D47104

Patent

active

047540389

ABSTRACT:
Histaminic H.sub.1 -receptor antagonists of the formula: ##STR1## in which R.sup.1 is ##STR2## where R.sup.2 is hydrogen, alkyl of 1 to 3 carbon atoms, alkoxy of 1 to 3 carbon atoms, halo, nitro, cyano or trifluoromethyl; and R.sup.3 is hydrogen, alkyl of 1 to 3 carbon atoms, alkoxy of 1 to 3 carbon atoms, halo, nitro, cyano or trifluoromethyl;

REFERENCES:
patent: 3502688 (1970-03-01), Berger et al.
patent: 3522262 (1970-07-01), Berger et al.
Herbert et al., J. Med. Chem. 23, 635 (1980).
Derwent Abstract 31,954 (U.S. Pat. No. 3,382,250).
Derwent Abstract 08747 (J5 5154-972).

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