Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1997-12-19
2000-05-30
Tsang, Cecilia J.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
424 8464, 435 686, 530380, A61K 37547, A61K 3702, C12N 1501, C07K 1300
Patent
active
060692340
ABSTRACT:
The present invention is directed to a modified coagulation factor Xa which has an improved capacity of forming crystals compared to its native form. Such crystals or crystalline composition are especially useful for studies in crystalline form of the active catalytic site of factor Xa when it is complexed to a specific affinity ligand with inhibiting characteristics.
REFERENCES:
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Chmielewska Joanna
Lundqvist Tomas
Masialou Erifili
Ogg Derek
Borin Michael
Pharmacia & UpJohn AB
Tsang Cecilia J.
Villacorta Gilberto M.
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