Indenoindoles and benzocarbazoles as estrogenic agents

Details Indenoindoles and benzocarbazoles as estrogenic agents Indenoindoles and benzocarbazoles as estrogenic agents

1999-05-06

2000-05-30

Stockton, Laura L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546200, 548420, 540602, 514212, 514410, A61K 31445, A61K 3140, A61K 3155, C07D40112, C07D40312

Patent

active

060691530

ABSTRACT:
The present invention relates to new substituted benzo[a]carbozoles and indenoindoles which are useful as estrogenic agents, as well as pharmaceutical compositions and methods of treatment utilizing these compounds, having the general structures below. ##STR1##

REFERENCES:
patent: 4656187 (1987-04-01), Black et al.
patent: 4894373 (1990-01-01), Young
patent: 4943572 (1990-07-01), von Angerer
patent: 5023254 (1991-06-01), von Angerer
patent: 5051442 (1991-09-01), Salituro et al.
patent: 5124335 (1992-06-01), Patchett et al.
patent: 5185360 (1993-02-01), Sainsbury et al.
patent: 5389641 (1995-02-01), Naka et al.
patent: 5395842 (1995-03-01), Labrie et al.
patent: 5496844 (1996-03-01), Inai et al.
patent: 5534527 (1996-07-01), Black et al.
patent: 5550107 (1996-08-01), Labrie
patent: 5552401 (1996-09-01), Cullinan et al.
patent: 5591753 (1997-01-01), Black et al.
patent: 5646137 (1997-07-01), Black et al.
patent: 5672609 (1997-09-01), Bryant et al.
patent: 5852039 (1998-12-01), Sohda et al.
von Angerer et al., J. Med. Chem.., vol. 33, No. 9, pp. 2635-2640, 1990.
von Angerer et al., J. Med. Chem., vol. 30, No. 1., pp. 131-136, 1987.
Rackeley, Contemporary Treatment in Cardiovascular Disease, 1, pp. 49-58 (1996).
von Angerer et al., Ann. N.Y. Aca. Sci., pp. 176, 177, 189, 1995.
Oparil "Hypertension in postmenopausal Women:Pathology and Management" EMBASE 95:283951, 1995.
von Angerer et al., J. Med. Chem. vol. 27, pp. 1439-1447, 1984.
Biberger, J. Steroid Biochem. Molec., vol. 58, No. 1, pp. 31-43 (1996).
Evans et al., Bone, vol. 17, No. 4, Oct. 1995, 181S-190S.
Von Angerer, J. Med. Chem. (1983), vol. 26 (1), pp. 113-116.
Kauppila et al., Am. J. Obstet. Gynecol., vol. 140, No. 7, 1981, pp. 787-792.
Kauppila et al., Arch. Gynecol. (1983) 234:49-58.
Segall et al., Eur. J. Med. Chem., 30, No. 2, 165-169 (1995).
Klinicheskaya Farmakologiya i Terapiya, 1996, 5 (1), pp. 70-75.
Klinicheskaya Farmakologiya i Terapiya, 1994, 3 (3), pp. 30-39.

Affiliated with

Also associated with

Rating

Indenoindoles and benzocarbazoles as estrogenic agents does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Indenoindoles and benzocarbazoles as estrogenic agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Indenoindoles and benzocarbazoles as estrogenic agents will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1910626