Carbostyril derivatives as combined thromboxane synthetase and c

Details Carbostyril derivatives as combined thromboxane synthetase and c Carbostyril derivatives as combined thromboxane synthetase and c

1986-05-29

1988-12-20

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546157, 546158, 546 13, 548335, 548337, C07D40106, C07D40110, C07D40112, A61K 3147

Patent

active

047925612

ABSTRACT:
The invention concerns a method of inhibiting both thromboxane synthetase and cyclic-AMP phosphodiesterase in a mammal having a disease characterized by elevated thromboxane levels or an imbalance of prostacyclin/thromboxane levels with a compound of the formula: ##STR1## or a pharmaceutically acceptable acid addition salt or ester thereof, wherein:

REFERENCES:
patent: 3962445 (1976-06-01), Buckle et al.
patent: 4309432 (1982-01-01), Tanaka et al.
patent: 4359475 (1982-11-01), Walker
patent: 4442106 (1984-04-01), Trijzelaar et al.
patent: 4455422 (1984-06-01), Banno et al.
patent: 4482560 (1984-11-01), Banno et al.
patent: 4487772 (1984-12-01), Tominaga et al.
patent: 4530930 (1985-07-01), Uno et al.
patent: 4608388 (1986-08-01), Kluge et al.
patent: 4728653 (1988-03-01), Campbell et al.
Chemical Abstract of Japan for Japan Patent 12384 (1/30/79).
Derwent Abstract No. 91173x for Japan Patent 118772 (10/18/76).
Derwent Abstract No. 94939x for Japan Patent 125291 (11/1/76).
Derwent Abstract No. 02856y for Japan Patent 136678 (11/26/76).
Derwent Abstract No. 11907y for Japan Patent 000283 (1/5/77).
Derwent Abstract No. 52426c for Japan Patent 076872 (6/10/80).
Derwent Abstract No. 93501e for Japan Patent 154129 (9/22/82).
Derwent Abstract No. 96290e for Japan Patent 159778 (10/1/82).
Derwent Abstract No. 83-786494 for Japan Patent 148817-A (9/5/83).
Derwent Abstract No. 83-786514 for Japan Patent 148861-A (9/5/83).
Derwent Abstract No. 84-168740 for Japan Patent 093-050-A (5/29/84).
Derwent Abstract No. 84-168742 for Japan Patent 093-052-A (5/29/84).

Affiliated with

Also associated with

Rating

Carbostyril derivatives as combined thromboxane synthetase and c does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Carbostyril derivatives as combined thromboxane synthetase and c, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Carbostyril derivatives as combined thromboxane synthetase and c will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1909714