Methods for inhibition of membrane fusion-associated events, inc

Details Methods for inhibition of membrane fusion-associated events, inc Methods for inhibition of membrane fusion-associated events, inc

1995-06-07

2000-05-30

Park, Hankyel

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

530324, 5303894, 4241471, 4242301, 4242061, C12Q 170, A61K 3800, A61K 3942, C07K 1600

Patent

active

060689730

ABSTRACT:
The present invention relates to peptides which exhibit potent anti-retroviral activity. The peptides of the invention comprise DP178 (SEQ ID:1) peptide corresponding to amino acids 638 to 673 of the HIV-1.sub.LAI gp41 protein, and fragments, analogs and homologs of DP178. The invention further relates to the uses of such peptides as inhibitory of human and non-human retroviral, especially HIV, transmission to uninfected cells.

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