Process for producing optically active titanium alkoxide complex

Details Process for producing optically active titanium alkoxide complex Process for producing optically active titanium alkoxide complex

1997-12-31

2000-02-15

Dentz, Bernard

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

556 54, 556 55, C07F 728

Patent

active

06025503&

ABSTRACT:
Disclosed is a process for producing novel optically active titanium alkoxide complexes which are excellent in catalytic activity and enantio-selectivity in carbon-carbon bond forming reactions (for example, Ene reaction, hetero-Diels-Alder reaction, Aldol reaction) and have high stability. The present process comprises reacting (R),(S),(RS)-catalysts or mixtures thereof selected from among optically active or racemic titanium alkoxide complexes represented by the following general formula (1), etc.: ##STR1## wherein R.sup.1 represents a methyl, lower alkoxy or trihalogeno group; R.sup.2 represents a hydrogen or halogen atom; R.sup.3 represents a hydrogen atom or a methyl group; and R.sup.4 represents a lower alkyl group, or R.sup.1 and R.sup.2 may form together a cyclo ring;
with chiral activators [(R),(S),(RS)-diols or mixtures thereof, but excluding reactions between a racemic modification and another racemic modification] to thereby activate exclusively one of the enantiomers.

REFERENCES:
patent: 5767295 (1998-06-01), Mitsuda et al.
Keck et al, Tet. Letters, vol. 34 (49), p.7827-7828, 1993.

Affiliated with

Also associated with

Rating

Process for producing optically active titanium alkoxide complex does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for producing optically active titanium alkoxide complex, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for producing optically active titanium alkoxide complex will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1907148