Process for preparing beta-anomer enriched 2-deoxy-2,2-difluoro-

Details Process for preparing beta-anomer enriched 2-deoxy-2,2-difluoro- Process for preparing beta-anomer enriched 2-deoxy-2,2-difluoro-

1992-06-22

1993-10-12

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549478, C07D30720

Patent

active

052527565

ABSTRACT:
A stereoselective process for preparing 2-deoxy-2,2-difluoro-D-ribofuranosyl beta-anomer enriched aryl sulfonates or substituted arylsulfonates involving reacting a lactol with an acid scavenger and a sulfonating reagent in an inert solvent.

REFERENCES:
patent: 4526988 (1985-07-01), Hertel
patent: 4965374 (1990-10-01), Chou et al.
Brewsfer & McEwen Organic Chemistry pp. 528-529, (1961).

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