Encainide N-oxide

Details Encainide N-oxide Encainide N-oxide

1980-06-19

1981-12-15

Milestone, Norma S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

424267, C07D21194

Patent

active

043060692

ABSTRACT:
4-Methoxy-N-[2-[2-(1-methyl-2-piperidyl)ethyl]phenyl]-benzamide N-oxide is an antiarrhythmic agent having reduced toxicity and increased water solubility relative to the corresponding tertiary amine.

REFERENCES:
patent: 3931195 (1976-01-01), Dykstra et al.
S. J. Dykstra et al., J. Med. Chem., vol. 16 (1973), pp. 1015-1020.
J. E. Byrne et al., J. Pharmacology and Experimental Therapeutics, vol. 200 (1977), pp. 147-154.

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