Process for preparing 24-fluoro-25-hydroxycholecalciferol

Details Process for preparing 24-fluoro-25-hydroxycholecalciferol Process for preparing 24-fluoro-25-hydroxycholecalciferol

1980-09-22

1981-12-15

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603972, 26023955R, C07J 900

Patent

active

043058809

ABSTRACT:
The invention provides a new derivative of vitamin D.sub.3, 24-fluoro-25-hydroxycholecalciferol.
The compound is characterized by vitamin D-like activity in its ability to increase intestinal calcium transport, increase serum calcium and inorganic phosphorous concentration and to prevent the development of rickets. It would find ready application as a substitute for vitamin D.sub.3 and in the treatment of disease states evincing calcium-phosphorous imbalance and which are nonresponsive to vitamin D.sub.3 therapy.

REFERENCES:
patent: 4226788 (1980-10-01), DeLuca et al.

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