Semi-synthetic lipopeptides, compositions containing said lipope

Details Semi-synthetic lipopeptides, compositions containing said lipope Semi-synthetic lipopeptides, compositions containing said lipope

1994-09-16

1996-05-14

Chan, Christina Y.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 9, 514 2, 530317, 930270, 930DIG548, 930DIG546, A61K 3812, C07K 764

Patent

active

055167578

ABSTRACT:
There are disclosed novel semi-synthetic lipopeptides of the formula (Seq. ID Nos. 1-6) ##STR1## wherein the substituents are defined herein, which show utility as antifungal and anti-Pneumocystis agents. Pharmaceutical compositions containing said compounds are also disclosed.

REFERENCES:
patent: 5166135 (1992-11-01), Schmatz
patent: 5378804 (1995-01-01), Balkovec et al.
Zambias, Journal of Medicinal Chemistry, vol. 35, pp. 2843-2855, (1992).
Walzer, et al., Diagn. Microbiol. Infect. Dis., vol. 2, pp. 1-6, 1984.

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