Diurea derivatives useful as medicaments and processes for the p

Details Diurea derivatives useful as medicaments and processes for the p Diurea derivatives useful as medicaments and processes for the p

1990-10-02

1992-02-25

Hollrah, Glennon H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

514595, 514597, 514598, 514585, 514586, 546309, 564 50, 564 52, 564 53, 564 54, 564 55, 564 56, 564 57, 564 59, 564 27, 564 26, A01N 3117

Patent

active

050914197

ABSTRACT:
Diurea derivatives are provided which are represented by the following general formula and salts thereof: ##STR1## The above compounds inhibit acyl-coenzyme A cholesterol acyl-transferase (ACAT enzyme), and thereby control the accumulation of cholesterol ester on the smooth muscle of arterial wall in the blood vessels.

REFERENCES:
patent: 3546344 (1970-12-01), Martin et al.
patent: 4127673 (1978-11-01), Yamada et al.
patent: 4159344 (1979-07-01), Teach et al.
patent: 4405644 (1983-09-01), Kabbe et al.
patent: 4473579 (1984-09-01), Devries et al.

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