Process for the manufacture of tetraalkyl ethenylidenebisphospho

Details Process for the manufacture of tetraalkyl ethenylidenebisphospho Process for the manufacture of tetraalkyl ethenylidenebisphospho

1989-01-24

1990-07-03

Sutto, Anton H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Phosphorus esters

558161, C07F 932

Patent

active

049392840

ABSTRACT:
Disclosed are tetraalkyl enthenylidenebisphosphonates and a method for their manufacture. These compounds are suitable for use as antimicrobial agents in combating a number of pathogenic microorganisms, such as bacteria, yeasts, viruses, fungi and protozoa, when used together with a pharmaceutically-acceptable carrier. Also disclosed is a method for treating infectious diseases by administering a safe and effective amount of these tetraalkyl ethenylidenebisphosphonates.

REFERENCES:
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patent: 3544509 (1970-12-01), Carroll et al.
patent: 3576793 (1971-04-01), Carroll et al.
patent: 3671644 (1972-06-01), Irani et al.
McIntosh et al., Can. J. Chem., vol. 56 (1978), pp. 226-231.
Patai et al., J. Org. Chem., vol. 25 (1960, pp. 1232-1234).
Semmalhack et al., J. Org. Chem., 43(6), pp. 1259-1262 (Mar. 1978).
Degenhardt et al., J. Org. Chem., 51(18), pp. 3488-3490 (Sep. 1986).

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