Monoclonal antibodies to human breast carcinoma cells and their

Details Monoclonal antibodies to human breast carcinoma cells and their Monoclonal antibodies to human breast carcinoma cells and their

1985-09-11

1990-07-03

Moskowitz, Margaret

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

43524027, 435948, 435 7021, 530389, 530808, 530809, 424 858, 424 8591, 424 11, 935104, 935107, C12N 5040, C07K 1504, A61K 4300, A61K 4505

Patent

active

049392409

ABSTRACT:
Monoclonal antibodies to adenocarcinoma cells, and, in particular, breast carcinoma cells, are produced by a hybridoma formed by fusing mouse lymphocytes and mouse myeloma cells. The monoclonal antibodies are capable of shrinking solid tumors associated with human breast. The monoclonal antibodies identify an antigen associated with carcinomas of ductal lineage. The monoclonal antibodies, specifically, F36/22 monoclonal antibodies, can be used diagnostically and therapeutically.

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