Viral inactivation process

Details Viral inactivation process Viral inactivation process

1988-12-20

1990-07-03

Foelak, Morton

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

C-o-group doai

424 86, 424 87, 424 88, 424 89, 530363, 530380, 530381, 530382, 530383, 530387, A61K 31045, A61K 3514, A61K 39104, A61K 39395

Patent

active

049391763

ABSTRACT:
Lipid-enveloped viruses present in purified biologically active protein products obtained from blood or cell culture systems can be inactivated by contacting the products with caprylic acid at a non-ionized concentration, pH, temperature and ionic environment sufficient to inactivate the viruses without adversely precipitating or affecting the biological activity of the protein products.

REFERENCES:
patent: 4440679 (1984-04-01), Fernandes et al.
patent: 4446134 (1984-05-01), Naito et al.
patent: 4481189 (1984-11-01), Prince
patent: 4495278 (1985-01-01), Thomas
patent: 4534972 (1985-08-01), Lembach
patent: 4762714 (1988-08-01), Mitra et al.
patent: 4834975 (1989-05-01), Siadak et al.
"New Immunotype Schema for Pseudomonas Aeruginosa Based on Protective Antigens", Fisher et al., Journal of Bacteriology, pp. 835-836, vol. 98, No. 2, May 1969.
"Anti-Microbial Agents and Chemotherapy", J. A. Sands et al., pp. 134-136, Jan. 1979.
Sequential Use of Fatty Acids, Horowitz et al., Vox. Sang., 54:14-20 (1988).
Precipitation of Plasma Proteins, Steinbuch et al., Biochem. Biophys., 134, 279-294 (1969).
IgG Recovery Using Caprylic Acid, Russo et al., J. Immunol. Methods, 65, 269-271 (1983).
Habeeb et al, Prep. Biochem., 14(1), 1-17 (1984).
Pejaudier et al., Vox. Sang., 23, 165-175 (1972).
Steinbuch, M. et al., Prep. Biochem., 3(4), 363-373 (1973).

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