Stereospecific resolution by hydrolysis of esters of 2-arylpropi

Details Stereospecific resolution by hydrolysis of esters of 2-arylpropi Stereospecific resolution by hydrolysis of esters of 2-arylpropi

1991-06-24

1992-12-29

Lilling, Herbert J.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing oxygen-containing organic compound

435134, 435135, 435141, 435197, 435280, C12P 740, C12P 764, C12N 918, C07P 4100

Patent

active

051751003

ABSTRACT:
2-Arylpropionic acids such as ketoprofen, ibuprofen and naproxen can be stereospecifically resolved from their esters by hydrolysis using liver enzymes and particularly liver acetone powders derived from specific animals such as dog, pigeon, horse and goat.

REFERENCES:
patent: 4650755 (1987-03-01), Wood
patent: 4800162 (1989-01-01), Matson
patent: 4857462 (1989-08-01), Maier et al.
patent: 4886750 (1989-12-01), Bertola et al.

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