Process for producing L-isoleucine by S-2-aminoethyl-L-cysteine

Details Process for producing L-isoleucine by S-2-aminoethyl-L-cysteine Process for producing L-isoleucine by S-2-aminoethyl-L-cysteine

1993-10-26

1995-10-24

Knode, Marian C.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing alpha or beta amino acid or substituted amino acid...

4352528, 435849, C12P 1306

Patent

active

054609585

ABSTRACT:
A process for the production of L-isoleucine using the microorganism, Escherichia coli H-8670 (FERM BP-4051) which has resistance to 0.2 g/l S-(2-aminoethyl)-L-cysteine or Escherichia coli H-8683 (FERM BP-4052) which has a resistance of 20 g/l of D-serine. The microorganism is cultured in a nutrient medium for a time and under conditions sufficient to produce L-isoleucine and the L-isoleucine is recovered from the medium.

REFERENCES:
Herrmann et al, (Ed.), Amino Acids: Biosynthesis and Genetic Regulation, Addison-Wesley Publishing Co.: London, 1983, pp. 415-416.
Inuzuka et al., "Fermentative Production of L-isoleucine", Chemical Abstracts vol. 87, No. 132324 1977.
Chemical Abstracts, vol. 89, No. 17, Oct. 23, 1978 No. 145017h.
Chemical Abstracts, vol. 83, No. 23, Dec. 8, 1975 No. 191345.

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