Vectors and compounds for expression of glycosylation mutants of

Details Vectors and compounds for expression of glycosylation mutants of Vectors and compounds for expression of glycosylation mutants of

1993-09-09

1995-10-24

Wax, Robert A.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

435212, 435 696, 4351723, 4352323, 43525233, 4353721, 4352402, 530380, 530381, 514 12, 536 232, 935 10, 935 14, 935 29, 935 70, 935 73, C12N 964, C12N 1557, C12N 1570, C12N 1579

Patent

active

054609534

ABSTRACT:
A method for the recombinant production of forms of human protein C with higher activity is described. These forms differ from native protein C in their increased amidolytic and functional activities and novel carbohydrate structures. DNA compounds, vectors, and transformants useful in the method are also disclosed.

REFERENCES:
patent: 4652639 (1987-03-01), Stabinsky
patent: 4775624 (1988-10-01), Bang et al.
patent: 4935349 (1990-06-01), McKnight
patent: 4959318 (1990-09-01), Foster et al.
patent: 4968626 (1990-11-01), Foster et al.
patent: 4992373 (1991-02-01), Bang et al.
patent: 5135854 (1992-08-01), MacKay et al.
patent: 5151268 (1992-09-01), Bang et al.
patent: 5270178 (1993-12-01), Gerlitz et al.
Fort Kamp, E., et al., 1986, DNA, 5(6):511-517.
Berg et al. (1989) Mol. Cell. Biol. 9(11), 5248-5253.
Grinnet et al. (1987) Bio/Technology 5, 1189-1192.
Madden et al. (1990) Thromb. Res. 53, 425-35 (Abstract only).
Toole et al. (1986) Proc. Natl. Acad. Sci. 83, 5939-5942.
Hau, L., and Salem, H., 1988, Thrombosis and Haemostasis 60:267-270.
Walls et al., Abstract and Slides from a presentation on "Role of Glycosylation in the Processing and Function of Recombinant Human Protein C" given at the UCLA Symposium in Keystone, Colorado in Apr., 1990.

Affiliated with

Also associated with

Rating

Vectors and compounds for expression of glycosylation mutants of does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Vectors and compounds for expression of glycosylation mutants of, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Vectors and compounds for expression of glycosylation mutants of will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1886032