Process for the selective preparation of monofluoro derivatives

Details Process for the selective preparation of monofluoro derivatives Process for the selective preparation of monofluoro derivatives

1996-07-11

1998-07-14

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

570124, 570127, 570128, 549518, 562852, 568484, 560125, 560145, 560100, 560105, C07C 6963, C07C 5158, C07C 4500, C07C 1908

Patent

active

057806721

ABSTRACT:
A process for the preparation of compounds of the formula (1) in which R.sup.1, R.sup.2 and R.sup.3 are as defined in the specification, which includes reacting alcohols or carboxylic acids of the formula (2) in which R.sup.1, R.sup.2 and R.sup.3 are as defined in the specification, with a fluorinating agent of the formula (3) as defined in the specification.

REFERENCES:
patent: 3137701 (1964-06-01), Ayer et al.
patent: 4833250 (1989-05-01), Bay
patent: 5442084 (1995-08-01), Lal
Liotta et al., "The Chemistry of Naked . . . Solvents", J. Am. Chem. Soc., 96:7, pp. 2250-2252, Apr. 1974.
Burton et al., "Tributylarsonium-2,2,3,3,4,4-hexa . . . Cleavage", J. Fluorine Chem., 18, pp. 413-416, Mar. 1981.
Burton et al., "Trialkylammonium-2,2,3,3,4,4 . . . Carbonion", J. Am. Chem. Soc., 99:14, pp. 4830-4831, Jul. 1977.
Rapp, "Reactions of Polyfluoro Olefins . . . Triethylamine", J. Am. Chem. Soc., 73, pp. 5901-5902, Dec. 1951.
Tetrahedron, 1996; vol. 52 (8); pp. 2977-2982, Corporate Research: Hoechst AG; Frankfurt; D-65926; Germany (DE), XP002016770, Pasenok S.V. et al. "New Method of Preparation of Fluoro Compounds via Utilization of Ammonium and Phosponium Perfluorocyclobutane Ylides as Fluorination Reagents".
J.T. Welch, Tetrahedron, vol. 43, No. 14 (1987) p. 3123.
G.B. Spero, et al., Steroids, vol. 11, Jun (1968) p. 769.
W.G. Young, et al., J. Am. Chem. Soc., vol. 82 Dec. 5, (1960) p. 6163.
R.L. Pruett, et al., J. Am. Chem. Soc., vol. 74 Apr. 5, (1952) p. 1633.
K.E. Rapp, et al., J. Am. Chem. Soc., vol. 72 (1950) p. 3646.

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