Use of 3,4-diphenyl chromans for the manufacture of a pharmaceut

Details Use of 3,4-diphenyl chromans for the manufacture of a pharmaceut Use of 3,4-diphenyl chromans for the manufacture of a pharmaceut

1997-07-08

1998-07-14

Henley, III, Raymond

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514422, A61K 3135, A61K 3140

Patent

active

057805024

ABSTRACT:
The present invention provides novel uses of compounds of general formula I ##STR1## wherein R.sup.1, R.sup.4 and R.sup.5 are individually hydrogen, hydroxy, halogen, trifluoromethyl, C.sub.1-6 alkyl, C.sub.1-6 alkoxy or (tertiary amino)( C.sub.1-6 alkoxy); and R.sup.2 and R.sup.3 are individually hydrogen or C.sub.1-6 alkyl, or a pharmaceutically acceptable salt thereof for the manufacture of a pharmaceutical composition for inhibiting one or more symptoms of premenstrual syndrome.

REFERENCES:
patent: 3822287 (1974-07-01), Bolger
patent: 4447622 (1984-05-01), Salman et al.
patent: 5280040 (1994-01-01), Labroo et al.
patent: 5453442 (1995-09-01), Bryant et al.
Joseph F. Mortola, M.D., "Pathophysiology and Treatment of Premenstrual Syndrome", 1995 Rapid Science Publishers ISSN 1068-3097, pp. 483-492.

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