Orally active phosphonyl hydroxyacyl prolines

Details Orally active phosphonyl hydroxyacyl prolines Orally active phosphonyl hydroxyacyl prolines

1986-01-06

1988-05-17

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546 22, 548414, C07F 965, A61K 31675

Patent

active

047451963

ABSTRACT:
This invention is directed to orally active antihypertensive agents of the formula ##STR1## wherein R.sub.1 is certain alkyl or aralkyl groups.

REFERENCES:
patent: 4452790 (1984-06-01), Karanewsky et al.
patent: 4452791 (1984-06-01), Ryono et al.
Rubin et al., SQ14,225 (D-3-Mercapto-2-Methylpropanoyl-L-Proline), . . . Jour. of Pharm. & Exp. Therapeutics, vol. 204, pp. 271-280.

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