Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1996-07-25
1998-07-14
Gupta, Yogendra N.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514255, 514256, 514269, 514272, 514274, 514340, 514345, 514348, 514349, 514351, 514352, 514357, 544238, 544405, 544297, 544298, 544310, 544316, 544317, 544319, 544321, 544322, 544324, 544327, 544331, 544333, 5462721, A61K 31525, A61K 31505, C07D40500, C07D40900
Patent
active
057804737
ABSTRACT:
Compounds of the formula ##STR1## inhibit the activity of endothelin.
REFERENCES:
patent: 2888455 (1959-05-01), Kano et al.
patent: 5236928 (1993-08-01), Chakravarty et al.
patent: 5270313 (1993-12-01), Burri et al.
patent: 5292740 (1994-03-01), Burri et al.
patent: 5378715 (1995-01-01), Stein et al.
patent: 5464853 (1995-11-01), Chan et al.
patent: 5571821 (1996-11-01), Chan et al.
patent: 5591761 (1997-01-01), Chan et al.
patent: 5594021 (1997-01-01), Chan et al.
patent: 5612359 (1997-03-01), Murugesan
S. Norio et al., Chemical Abstracts, vol. 70, No. 19, (1969), 87639g.
T. Saito, Chemical Abstracts, vol. 73, No. 23 (1970), 120511w.
Derwent Abstract No. 88-289069/41, Feb. 27, 1987.
Derwent Abstract No. 88-195835/28, Nov. 26, 1986.
Derwent Abstract No. 88-061295/09, Jul. 9, 1986.
Derwent Abstract No. 87-152485/22, Oct. 11, 1985.
Derwent Abstract No. 62299 E/30, Dec. 11, 1980.
Derwent Abstract No. 40927 D/23, Sep. 11, 1979.
Derwent Abstract No. 91-254550/35, Feb. 19, 1990.
Derwent Abstract No. 86-246709/38, Nov. 27, 1985.
Derwent Abstract No. 35012 K/15, Sep. 24, 1981.
Allen et al., "Preparation . . . antagonists", CA116(11):106284Z, p. 778, 1992.
Chan et al., "Identification of a New Class of ET.sub.A Selective Endothelin Antagonists by Pharmacophore Directed Screening", Biochemical and Biophysical Research Communications, vol. 201, No. 1, May 30, 1994, pp. 228-234.
Doherty, J. Med. Chem., 35(9), 1493-1508 (May 1992).
CA 65: 2241d (1966).
CA 92:41908v (1979).
Wang et al., "Nitrile . . . sinomin," CA 108:94444w, p. 651 (1988).
Khanna, "Oral . . . formulation," CA 115:35728p, p. 415 (1991).
Stein et al., "The Discovery . . . 1-naphthalenesulfonamide," CA 120:18233n, pp. 21-22 (1994).
Vree et al., "Renal excretion . . . function," CA 97:84685r, p. 23 (1982).
Oie, "Pharmacokinetics . . . dosing," CA102:1917512x, p. 18 (1985).
Murugesan et al., "N-(heteroaryl) . . . antagonists," CA 120:270370c, p. 1067 (1994).
Barrish Joel C.
Murugesan Natesan
Stein Philip D.
Babajko Suzanne E.
Bristol--Myers Squibb Company
Gupta Yogendra N.
LandOfFree
Substituted biphenyl sulfonamide endothelin antagonists does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Substituted biphenyl sulfonamide endothelin antagonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted biphenyl sulfonamide endothelin antagonists will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1882015