Melatonergic indanyl piperazines

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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Details

514252, 514255, 544336, 544404, A01N 4360, A61K 31495

Patent

active

057804702

ABSTRACT:
Certain indanyl piperazines are useful as melatonergic agents and can treat various CNS disorders. They are use useful in treating sleep disorders and other conditions related to circadian rhythms.

REFERENCES:
patent: 4963680 (1990-10-01), Manoury et al.
Dubocovich, et al., "Antidepressant-like activity of the melatonin receptror antagonist, luzindole (N-0774), in the mouse behavioral despair test," European Journal of Pharmacology., 182: 313-325 (1990).

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