Substituted quinazoline-3-oxides providing pharmacological activ

Details Substituted quinazoline-3-oxides providing pharmacological activ Substituted quinazoline-3-oxides providing pharmacological activ

1986-06-05

1988-05-17

Hollrah, Glennon H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

5142328, 5142348, 514267, 544116, 544250, 544283, A61K 3100, C07D41300

Patent

active

047451181

ABSTRACT:
Novel substituted quinazoline-3-oxides are disclosed as are methods of increasing cardiotonic activity and bronchodilation in which an unit dose of a composition containing an effective amount of a cardiotonic agent or a bronchodilating agent dispersed in a pharmaceutically acceptable carrier are administered to a mammalian host.

REFERENCES:
Brown, Heterocyclic Compounds, Fused Pyrimidines, Part 1, 1967, John Wiley & Sons, N.Y., pp. 450-452.
Fey, et al., "Chemical Abstracts", vol. 67(18), 1967, Col. 86253c.
T. Higashino, Chem. Pharm. Bull. Japan (1961) 9, 635.
Zenno, et al., Chemical Abstracts, vol. 70, (1969), Col. 28944c.
Zenno, et al., Chemical Abstracts, vol. 72, (1970), Col. 90506h.

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