Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical
Patent
1996-07-17
1998-07-14
Horlick, Kenneth R.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing compound containing saccharide radical
435 6, 4353201, 435810, 536 221, 536 237, C12P 1934, C07H 2104, C12Q 168, C12N 1509
Patent
active
057802700
ABSTRACT:
Methods, kits, and reagents for conducting site-specific mutagenesis of single or double-stranded nucleic acids which utilizes novel antibiotic resistance conferred by a mutated antibiotic resistance gene for efficient mutant selection are described.
REFERENCES:
patent: 4521509 (1985-06-01), Benkovic et al.
patent: 4873192 (1989-10-01), Kunkel
patent: 5071743 (1991-12-01), Slilaty
Venkatachalam et al., Characterization of TEM-1 bata-lactamase mutants from positions 238-241 with increased catalytic efficiency for ceftazidime, J. Biol. Chemistry, vol. 269(38), pp. 23444-23450, 1994.
Bohnsack (1996), Methods in Molecular Biology; In vitro Mutagenesis Protocols; vol. 57, M.K. Thrower, Ed, Humana Press Inc., Totowa, New Jersey.
Current Protocols in Molecular Biology (1994), vol. 1, Chapter 1.8, John Wiley and Sons, New York, New York.
Delaire, M., Labia, R., Samama, J.P., and Masson, J.M. (1992), The Journal of Biological Chemistry 267(29): 20600-20606.
Hanahan, D. (1985), In: DNA Cloning, vol. 1, Glover, ed., IRL Press Ltd., London, 109.
Imtiaz et al. (1994), Antimicrobial Agents and Chemotherapy, (38)5: 1134-1139.
Lenfant et al. (1991), The Journal of Biological Chemistry, 266(26):17187-17194.
Palzkill and Botstein (1992a), Proteins: Structure, Function, and Genetics, 14:29-44.
Palzkill and Botstein (1992b), Journal of Bacteriology, 17:5237-5243.
Vandeyar et al. (1988), Gene, 65:129-133.
Venkatachalam et al. (1994), Characterization of TEM-1 .beta.-lactamase Mutants From Positions 238 to 241 With Increased Catalytic Efficiency For Ceftazidime, The Journal of Biological Chemistry, 269(38): 23444-23450.
Horlick Kenneth R.
Promega Corporation
Tung Joyce
LandOfFree
Site-specific mutagenesis and mutant selection utilizing antibio does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Site-specific mutagenesis and mutant selection utilizing antibio, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Site-specific mutagenesis and mutant selection utilizing antibio will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1880788