Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1995-06-06
1998-07-14
Walsh, Stephen
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4352523, 4353201, 435325, 536 235, C12N 1512
Patent
active
057802637
ABSTRACT:
A human Small CCN-Like Growth Factor polypeptide (SCGF) and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for wound healing or tissue regeneration, stimulating implant fixation and angiogenesis. Antagonist against such polypeptides and their use as a therapeutic to treat atherosclerosis, tumors and scarring are also disclosed. Diagnostic assays for identifying mutations in SCGF nucleic acid sequences and altered levels of the SCGF polypeptide are also disclosed.
REFERENCES:
FEBS 12753, vol. 327, No. 2, Bork, issued Jul. 1993, pp. 125-130.
Genomics, vol. 16, Chen, et al., issued 1993, pp. 533-535.
Journal of Cell Biology, vol. 114, No. 6, issued Sep. 1991, Bradham, et al., pp. 1285-1294.
Proc. Natl'l. Acad. Sci. USA, vol. 86, issued Feb. 1989, Simmons, et al., pp. 1178-1182.
EMBL-Genbank, pub. May 18, 1995, Hillier, et al., Locus R52804.
EMBL-Genbank, pub. Jan. 4, 1995, Adams, et al., Locus T31748.
EMBL-Genbank, pub. Jan. 4, 1995, Adams, et al., Locus T31716.
EMBL-Genbank, pub. Nov. 6, 1994, Genexpress, Locus HSC29F031.
EMBL-Genbank, pub. Jun. 4, 1993, Genexpress, Locus HSA06A062.
Adams Mark D.
Hastings Gregg A.
Brown Karen E.
Human Genome Sciences Inc.
Mullins J. G.
Olstein Elliot M.
Walsh Stephen
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