Indole containing, 2-thienyl-1,2,3,6-tetrahydropyridyls and thei

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546273, C07D40914

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active

048700878

ABSTRACT:
Indole derivatives of the general formula I ##STR1## in which Ind is a 3-indolyl radical which can be substituted once or twice by alkyl, O-alky, S-alkyl, SO-alkyl, SO.sub.2 -alkyl, OH, F, Cl, Br, CF.sub.3 and/or CN or by a methylenedioxy group, A is --(CH.sub.2).sub.4 -- or --CH.sub.2 --L--CH.sub.2 CH.sub.2 --, L is --S--, --SO-- or --SO.sub.2 --, and Th is a 2-- or 3-thienyl radical, and in which the alkyl groups each have 1-4 C atoms, and their physiologically acceptable acid addition salts exhibit effects on the central nervous system.

REFERENCES:
patent: Re28973 (1976-09-01), Welstead
patent: 3639414 (1972-02-01), Archer et al.
patent: 3642803 (1972-02-01), Welstead
patent: 3686213 (1972-08-01), Poletto et al.
patent: 4251538 (1981-02-01), Hausberg et al.
patent: 4478841 (1984-10-01), Audiau et al.
Minot et al., CA. 94 : 64902U.
Nedelec et al., CA 96 : 35100S equivalent to Fr. 2470128.

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