Process for production of diltiazem hydrochloride

Details Process for production of diltiazem hydrochloride Process for production of diltiazem hydrochloride

1984-04-16

1985-11-12

Bond, Robert T.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

549548, 549549, 549555, 560 17, C07D28102

Patent

active

045526958

ABSTRACT:
New route to diltiazem hydrochloride of the formula: ##STR1## in which the starting cinnamyl alcohols are epoxidized by a special asymmetric synthesis followed by a series of stereospecific reactions; no optical resolution is required at any stage.

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