Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1996-10-29
1998-02-24
Owens, Amelia A.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549264, A61K 31335
Patent
active
057212716
ABSTRACT:
Compounds of formula (I): ##STR1## wherein R.sup.1 is hydrogen or methyl, R.sup.2 is hydrogen or (E)-2-methyl 2-butenoyloxy, and R.sup.3 is hydrogen or hydroxy, with the proviso that when R.sup.3 is hydrogen, R.sup.1 and R.sup.2 are both hydrogen, and when R.sup.2 is (E)-2-methyl 2-butenoyloxy, R.sup.1 is methyl; the compound of formula (II): ##STR2## and the compound of formula (III): ##STR3## are obtainable by the fermentation of Streptomyces E225 NCIB 12310 or Streptomyces E225B NCIB 12509. The compounds have anthelmintic utility.
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patent: 4093629 (1978-06-01), Fisher
patent: 4144352 (1979-03-01), Putter
patent: 4310519 (1982-01-01), Albers-Schonberg et al.
J. Antibiotics, 1976, 29(3):76-14 to 76-16.
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Baker Geoffrey Harold
Banks Rhona Mary
Dorgan Roderick John
Poulton Mark Edward
Ginsburg Paul H.
Koller Alan L.
Owens Amelia A.
Pfizer Inc.
Richardson Peter C.
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