Process for the preparation of pyridine-2-3-dicarboxylic acid de

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

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546113, 546116, 546193, 546194, 546281, 546291, 546296, 546297, 546299, 546306, 546316, 546321, 546250, C07D213803, C07D21382, C07D47104, C07D491048

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047482443

ABSTRACT:
The invention relates to a process for the preparation of pyridine-2,3-dicarboxylic acid derivatives of formula ##STR1## which process comprises reacting a hydrazone of formula II ##STR2## with a maleic acid derivative of formula III ##STR3## to give a 1-amino-1,4-dihydropyridine-2,3-dicarboxylic acid derivative of formula IV ##STR4## and subsequently removing R.sub.9 R.sub.10 NH. In the above formulae, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.9, R.sub.10 and X are as defined in claim 1. The pyridine-2,3-dicarboxylic acid derivatives of formula I are intermediates for the preparation of herbicidal compounds.

REFERENCES:
patent: 3027380 (1962-03-01), Leonard et al.
patent: 4439607 (1984-03-01), Drabb
Cochran, J. L. et al, J. Org. Chem 26, pp. 808-811 (1961).
Oakes, V. et al, J. Chem. Soc. 1956, pp. 4433-4438.

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