Preparation of 2-chloro-5-chloromethylthiazole

Details Preparation of 2-chloro-5-chloromethylthiazole Preparation of 2-chloro-5-chloromethylthiazole

1987-08-31

1988-05-31

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548205, C07D27732

Patent

active

047482435

ABSTRACT:
A process for the preparation of 2-chloro-5-chloromethyl-thiazole of the formula: ##STR1## comprising reacting allyl isothiocyanate of the formula

REFERENCES:
patent: 4013674 (1977-03-01), Beck
Metzger, Thiazole and its Derivatives, pp. 273-274 (1979).
E. Kuhle, B. Anders and G. Zumach; Isocyaniddihalogenidynthesen-Syntheses, Chemie 79, 663 (1967).
J. Amer. Chem. Soc. 56, pp. 470-471, J. Amer. Chem. Soc. 104, pp. 4461-4465, J. Amer. Chem. Soc. Perkin I, 1982, pp. 159-164.

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