Recombinant asparaginyl-tRNA synthetase from the human filarial

Details Recombinant asparaginyl-tRNA synthetase from the human filarial Recombinant asparaginyl-tRNA synthetase from the human filarial

1996-04-09

1998-02-24

Housel, James C.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 6, 435 723, 536 232, 935 76, 935 77, G12P 2106

Patent

active

057211167

ABSTRACT:
Recombinant asparaginyl tRNA synthetase from human filarial parasite Brugia malayi. The enzyme is used in an assay for inhibitors of the synthetase and can be used as an antigen for producing antibody inhibitors of the disease, either monoclonal or polyclonal. The antibodies can be used to detect the synthetase and related enzymes. In particular, the synthetase can be used to produce an antibody to be used for detecting filarial nematodes. The synthetase can be used to produce adenylated nucleosides.

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