Bis-esters of methanediol with penicillins and penicillanic acid

Details Bis-esters of methanediol with penicillins and penicillanic acid Bis-esters of methanediol with penicillins and penicillanic acid

1980-09-08

1983-03-22

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424270, 424271, C07D49900, A61K 31425

Patent

active

043775241

ABSTRACT:
6'-Acylaminopenicillanoyloxymethyl esters of penicillanic acid 1,1-dioxide are useful as antibacterial agents. The 6'-aminopenicillanoyloxymethyl ester, halomethyl esters, alkylsulfonyloxymethyl esters and arylsulfonyloxymethyl esters of penicillanic acid 1,1-dioxide are all useful intermediates for the aforesaid antibacterial agents.

REFERENCES:
patent: 3838152 (1974-09-01), Hou et al.
patent: 3850908 (1974-11-01), von Paehne et al.
patent: 3869449 (1975-03-01), Godtfredsen
patent: 3981865 (1976-09-01), Saikawa et al.
patent: 4051126 (1977-09-01), Murakami et al.

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