Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3

Details Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3 Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3

1981-02-20

1982-08-17

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546 90, 546141, 546142, 546147, A61K 3147, C07D21716, C07D491048

Patent

active

043449492

ABSTRACT:
Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids and the pharmaceutically acceptable salts thereof are produced by coupling a suitably substituted 1,2,3,4-tetrahydroisoquinoline with a suitably substituted amino acid and when desired hydrolyzing or removing protecting groups of the resulting product. The compounds of the invention, their salts and pharmaceutical compositions thereof are useful as antihypertensive agents.

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