Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Separation or purification
Patent
1995-05-25
1996-07-09
Jones, W. Gary
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Separation or purification
435 6, 435174, 435177, 435181, 436501, 436543, 530412, 530344, 530345, C07K 122, C12N 1100, C12N 1106, G01N 33547
Patent
active
055346200
ABSTRACT:
A novel heterogenous purification method is disclosed. The method removes a macromolecule from a liquid by allowing the macromolecule to undergo a specific binding affinity reaction with a bidentate conjugate. The method is carried out by immobilizing the bidentate conjugate on a solid phase, contacting the bidentate conjugate with the liquid comprising the macromolecule, and separating the immobilized bidentate conjugate from contact with the liquid, thereby removing the macromolecule from the liquid to obtain either purified macromolecule or a purified liquid.
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Kearns Elizabeth K.
Oh Chan S.
Beckman Instruments Inc.
Hampson Gary T.
Jones W. Gary
May William H.
Tran Paul B.
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