Stopper assembly having bypass features for use in a multi-chamb

Details Stopper assembly having bypass features for use in a multi-chamb Stopper assembly having bypass features for use in a multi-chamb

1997-11-06

1999-05-04

Yasko, John D.

Surgery

Means for introducing or removing material from body for...

Treating material introduced into or removed from body...

604 82, 604218, A61M 500

Patent

active

058998810

ABSTRACT:
A stopper assembly having by-pass features for use in a multi-chamber syringe barrel. The stopper assembly includes a sequential stopper body responsive to fluid forces for enabling the sequential delivery of disparate contents, such as disparate fluids, separately held in the syringe barrel. The sequential stopper body has a generally cylindrical sidewall with a distal end, a proximal end and a longitudinal axis therethrough. The stopper assembly also includes a generally cylindrical flow channelizer mounted to the distal end of the sequential stopper body. The flow channelizer enables the reconstitution of dry medicament held in the syringe barrel distally of the flow channelizer. The flow channelizer features opposed proximal and distal ends and a generally cylindrical outer surface therebetween. At least one fluid flow channel extends between the proximal and distal ends of a flow channelizer. A distally directed, conically-shaped projection is located at the distal end of the flow channelizer to prevent the accumulation of dead space between the channelizer and the internal shoulder located at the distal end of the syringe barrel. The stopper assembly may be employed in a multi-chambered syringe barrel featuring a by-pass channel to permit fluids to pass distally of the stopper assembly. The multi-barreled syringe barrel can be separated into disparate chambers by one or more by-pass stoppers so as to contain disparate components intended for sequential delivery by the stopper assembly.

REFERENCES:
patent: 3331538 (1967-07-01), Higgins
patent: 3957051 (1976-05-01), Topham
patent: 4465476 (1984-08-01), Gahwiler
patent: 4599082 (1986-07-01), Grimard
patent: 4929230 (1990-05-01), Pfleger
patent: 5489266 (1996-02-01), Grimard
patent: 5599312 (1997-02-01), Higashikawa
patent: 5685845 (1997-11-01), Grimard
patent: 5704918 (1998-01-01), Higashikawa
patent: 5713857 (1998-02-01), Grimard et al.

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