Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1979-12-26
1981-06-02
Randolph, John D.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
546257, A61K 3144, C07D21357
Patent
active
042711681
ABSTRACT:
3-Acylamino-5-[4(or 3)-pyridinyl]-2(1H)-pyridinones or pharmaceutically-acceptable acid-addition salts thereof useful as cardiotonic agents are prepared by reacting the corresponding 3-amino compound with an acylating agent providing acyl, where acyl is 2-acetoxypropanoyl, acetoacetyl or acetoxyacetyl. Cardiotonic compositions and method for increasing cardiac contractility using said 3-acylamino compounds as active component are disclosed.
REFERENCES:
patent: 4004012 (1977-01-01), Lesher et al.
patent: 4072746 (1978-02-01), Lesher et al.
patent: 4107315 (1978-08-01), Lesher et al.
Lesher George Y.
Opalka, Jr. Chester J.
Bair Robert K.
Randolph John D.
Sterling Drug Inc.
Wyatt B. Woodrow
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