Melatonin antagonist

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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A61K 31405

Patent

active

048808261

ABSTRACT:
The invention relates to novel derivatives of melatonin, to the production of such new derivatives, to labelled forms, and especially radioactively tagged forms of such compounds, to assays for melatonin receptor function based on such radioactively tagged compounds and to pharmaceutical compositions which contain such novel non-labelled compounds.
The novel compounds are potent antagonists of melatonin which are of value in human medicine and also in animal husbandry.

REFERENCES:
Chem. Abstr., 108-32414c (1988).
Biochemistry, 13(18), pp. 3816-3827 (1974).

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