Use of C-5 mono-substituted barbiturates to treat disorders of u

Details Use of C-5 mono-substituted barbiturates to treat disorders of u Use of C-5 mono-substituted barbiturates to treat disorders of u

1987-06-24

1989-11-14

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514825, A61K 31515

Patent

active

048808113

ABSTRACT:
The present invention provides a method for decreasing the bodily content of uric acid in a subject which comprises administrating to the subject an effective content-decreasing amount of a barbiturate compound mono-substituted at the carbon-5 position.
The invention also provides a pharmaceutical composition and a method for treating disorders of uric acid metabolism and resulting ailments in a subject.

REFERENCES:
patent: 4634707 (1987-01-01), Brewer et al.
The Pharmacological Basis of Therapeutics, 4th edition, D. M. Woodbury, 1970, pp. 341-347.
Arthritis and Allied Conditions, J. L. Hollander et al, 1972, pp. 1071-1111, 1112-1139.

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