Antimicrobial preparation

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514970, A61K 31545

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active

048807966

ABSTRACT:
An antimicrobial preparation of D-7-[.alpha.-(4-hydrooxy-6-methylnicotinamido)-4-hydroxyphenylacetamido]-3 -(1-methyltetrazol-5-yl)thiomethyl-.DELTA..sup.3 -cephem-4-sodium carboxylate (hereinafter referred to as "Compound A" of enhanced stability is disclosed, which comprises a microbially effective amount of Compund A and a stabilizer selected from the class consisting of benzoic acid, sodium benzoate and nicotinamide.

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patent: 4390535 (1983-06-01), Yamada et al.
Remington Pharmaceutical Sciences, 16, p. 1367 (1980).
Drugs of the Future, vol. 5(5), pp. 254-255 (1980).
The Merck Index, 9th ed., pp. 142-143 and 1109 (1976).
Pharmazie, 24, 155-157 (1969) W/Abstract [Ring Doc. Profile (Derwent Co.)].

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