Antiinflammatory carbinolamine esters of 1,2,4-triazoles

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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548262, A61K 3141, C07D24908

Patent

active

043328121

ABSTRACT:
Carbinolamine esters of 1,2,4-triazoles are provided having the structure ##STR1## wherein R, R.sup.1, R.sup.2 and R.sup.3 are as defined herein. These compounds are useful as antiinflammatory agents.

REFERENCES:
patent: 4006159 (1977-02-01), Newman
patent: 4154841 (1979-05-01), Wade et al.
patent: 4169148 (1979-09-01), Wade et al.
"A Novel Synthesis for 3-Substituted 1,2,4--Triazoles," Journal fur praktische Chemie, vol. 311, 1969, pp. 477-489, Becker et al.
"Reactions of Aromatic Amide Carbamylhydrazones with Acetic Anhydride," Ikizler et al., Chem. Abstracts, vol. 86, Abstract No. 55351w (1977).

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