Process for treating hyperglycemia using trifluoromethyl substit

Details Process for treating hyperglycemia using trifluoromethyl substit Process for treating hyperglycemia using trifluoromethyl substit

1992-04-07

1993-11-23

Ramsuer, Robert W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514407, 514866, 5483661, A61K 31415

Patent

active

052644510

ABSTRACT:
The compound of the formula: ##STR1## in which the dotted lines represent two sites of unsaturation appropriately located based on the identity of R.sup.2, R.sup.3 and R.sup.4 and, R.sup.1 is alkyl, perfluoroalkyl, alkoxy, perfluoroalkoxy, alkylthio, perfluoroalkylthio, alkylsulfinyl, alkylamino, halo, alkanoyl, 1-hydroxyalkyl or (1-hydroxyimino) alkyl; R.sup.2 is hydrogen or alkyl; R.sup.3 is hydrogen or alkyl; R.sup.4 is hydrogen or alkyl; n is 0 or 1; or a pharmaceutically acceptable salt thereof, are antihyperglycemic agents.

REFERENCES:
patent: 3978077 (1976-08-01), Moller et al.
patent: 4099011 (1978-07-01), Moller et al.
patent: 4113957 (1978-09-01), Moller et al.

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