Process for the O-methylation of hydroxyaporphines

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D22118

Patent

active

043095429

ABSTRACT:
A process for the O-methylation of hydroxyaporphines is disclosed. This process utilizes a trimethylphenylammonium base as the alkylating agent.

REFERENCES:
patent: 1100998 (1914-06-01), Traub
Bently, The Chem. of the Morphine Alkaloids, pp. 303 & 307.
Bently "The Chem. of the Morphine Alkaloids, pp. 59, 60, Clarendon Press, Oxford, (1954).
Spath, et al., Beuichte, 62, pp. 325-331, (1929).
Bull. Soc. Chim. 39, p. 305, (1926).

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