Substituted pyrazinyl-1,2,4-oxadiazoles

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

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424250, C07D24114, A61K 3150

Patent

active

043095402

ABSTRACT:
Novel substituted pyrazinyl-1,2,4-oxadiazoles and processes for preparing the same. The compounds are useful in the treatment of edema and hypertension.

REFERENCES:
patent: 3313813 (1967-04-01), Cragoe, Jr.
Cragoe, et al., "J. Med. Chem.", vol. 10 (1967), pp. 66-75.
Watthey, et al., "J. Med. Chem.", vol. 23, (1980), 690-692.
Cecil et al., "A Textbook of Medicine", (1957), p. 1251.
Adams, et al, "J. Org. Chem.", vol. 18 (1953), p. 934.
Eloy, "Fortschr. Chem. Forsch", vol. 4 (1965), p. 807.
Clapp, "Adv. Het. Chem", vol. 20 (1976), p. 65.
Warburton, "J. Chem. Soc.", (1966), p. 1522.
Strani et al., "Gazz. Chim. Ital.", vol. 93, (1963), 482.

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