Method for decreasing the appetite in bulimic, overweight indivi

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514546, 514547, 514552, A01N 4338

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active

060666641

ABSTRACT:
A method for controlling and decreasing the appetite in an overweight individual is disclosed which comprises administering to said individual 5-hydroxytryptophan and an alkanoyl L-carnitine wherein the alkanoyl group has 2-6 carbons atoms, preferably acetyl L-carnitine, or a pharmacologically acceptable salt thereof.

REFERENCES:
patent: 3810994 (1974-05-01), Wiegand
Fletcher et al., "Dissociation of the anorectic action s of 5-HTP and fenfluramine", Psychopharmacology (Berlin), 89(2), pp. 216-220, 1986, see abstract; 1986.
P. Borum, "1.sup.st. Meeting on Nutrition in Childhood, Carnitine's Biological Role in Childhood", Clinica Pediatrica V Istituto Di Scienze Biomediche Ospedale S. Paolo-Milano, Milano Nov. 27-28, 1986.
1991 David W. Smith Workshop on Malformations and Morphogenesis, "Prevalence of Lipid Storage Myopathy in the Macrocephaly Syndromes: Clinical Correlations and Outcome of Carnitine Therapy", Sep. 27-Oct. 1, 1991.
Clampagila et al, "Effect of L-carnitine of protein catabolic rate in chronic hemodialysis patients", Journal of The American Society of Nephrology, vol. 8, 1997.
Paul J. Fletcher et al, "Dissociation of the anorectic actions of 5-HTP and fenfluramine", Psychopharmacology, vol. 89, pp. 216-220, 1986.

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