Inhibitors of microsomal triglyceride transfer protein and metho

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514248, 514252, 514266, 514307, 514314, 514318, 514320, 514321, 514322, 514323, 514324, 514326, 514329, 544235, 544238, 544277, 544407, 546146, 546169, 546194, 546196, 546197, 546198, 546199, 546201, 546202, 546208, 546209, 546211, 546213, 546214, 546223, 546224, A61K 31445, A61K 3147, A61K 3152, A61K 31495, C07D21100, C07D21700, C07D21538, C07D40100

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active

060666501

ABSTRACT:
Compounds are provided which inhibit microsomal triglyceride transfer protein and thus are useful for lowering serum lipids and treating atherosclerosis and related diseases. The compounds have the structure ##STR1## wherein R.sup.1 to R.sup.7, Q, X and Y are as defined herein.

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