Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1997-06-10
2000-05-23
Celsa, Bennett
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 694, 435 6952, 530300, 530311, 530331, 530343, 530350, 530351, 530399, C12P 2106, C07K 1107, C07K 112
Patent
active
060664703
ABSTRACT:
The present invention provides a method for chemically removing a N-terminal methionine residue selectively, specifically and efficiently from a peptide or a salt thereof having an optionally oxidized methinine residue at its N-terminal. The method reacts a peptide or a salt thereof having an optionally oxidized methinine residue at its N-terminal with an .alpha.-diketone derivative, followed by hydrolysis.
REFERENCES:
Abstract for EP 97 30 3856, dated Sep. 30, 1997, included in European Search Report.
Derwent AN 95-038217 to JP 06 316 557 Nov. 15, 1995.
Caplus Abstract No. 1995: 380330 of JP06316557 Nov. 15, 1994 with Displayed Structures from Reg No.
Nishimura Osamu
Ohmae Hiroaki
Suenaga Masato
Tsuji Shinji
Celsa Bennett
Conlin David G.
Takeda Chemical Industries Ltd.
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