Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1977-12-14
1978-10-31
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
260287AN, 260287CF, 560 22, 560 44, A61K 3147, C07D21556
Patent
active
041235363
ABSTRACT:
The present invention relates to dialkyl ({[3-(alkoxy-carbonyl)-1,4-dihydro-4-oxo-8-quinolinyl]amino}methylene)-pro panedioates having the following structural formula: ##STR1## wherein R.sub.1 is lower alkyl; and R.sub.2 is hydrogen, halogen, lower alkyl or nitro.
These compounds exhibit antibacterial activity against gram positive and gram negative bacteria and are therefore useful in the treatment of bacterial infections caused by these organisms.
REFERENCES:
patent: 3790577 (1974-02-01), Waring
Snyder et al., "J. Am. Chem. Soc." 68:1320-1322, (1946).
Connor David T.
VON Strandtmann Maximilian
Young Patricia A.
Chow Frank S.
Daus Donald G.
Graddis Albert H.
Kelly Anne M.
Warner-Lambert & Company
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